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Oral Anticoagulation Reversal
Oral Anticoagulation Reversal Learning Zone

Expert Insights

Read time: 60 mins
Last updated:31st Oct 2023
Published:27th Feb 2020

A small but notable number of patients receiving oral anticoagulation will experience a major bleed or require invasive surgery. In these situations, anticoagulation reversal is often essential, but how should reversal be managed in these patients? How should it differ between patients receiving a vitamin K antagonist (VKA), and a non-vitamin K antagonist oral anticoagulant (NOAC)?

Join Professor Donat Spahn, Professor Thorsten Steiner and Dr Oliver Grottke as they discuss best practice in the management of oral anticoagulation reversal.

Oral anticoagulation reversal roundtable discussion 

Reversing warfarin part 1: plasma or PCC?

Do the panel think there is still a role for fresh frozen plasma (FFP) in anticoagulation reversal?

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

Do the panel think there is still a role for fresh frozen plasma (FFP) in anticoagulation reversal?

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

Reversing warfarin part 2: outcomes with PCCs

PCCs effectively reverse warfarin anticoagulation – but how do 3- and 4-Factor PCCs compare?

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

PCCs effectively reverse warfarin anticoagulation – but how do 3- and 4-Factor PCCs compare?

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

Reversal of NOACs part 1: direct factor Xa inhibitors

How would the panel manage reversal in patients taking direct factor Xa inhibitors?

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

How would the panel manage reversal in patients taking direct factor Xa inhibitors?

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

Reversal of NOACs part 2: direct factor IIa inhibitors

Join the panel as they discuss the recent approval, and use of, specific factor IIa reversal agents.

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

Join the panel as they discuss the recent approval, and use of, specific factor IIa reversal agents.

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

Recommendations for clinical practice - Case study 1

How would the panel manage an elderly patient receiving warfarin who experiences syncope and contusive head trauma?

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

How would the panel manage an elderly patient receiving warfarin who experiences syncope and contusive head trauma?

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

Recommendations for clinical practice - Case study 2

A patient receiving a NOAC has an ICH – join the panel as they discuss how they would manage this patient.

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

A patient receiving a NOAC has an ICH – join the panel as they discuss how they would manage this patient.

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

Anticoagulation and bleeding risk

What factors influence a patient’s risk of bleeding on anticoagulation therapy? Join the panel as they discuss the bleeding risks associated with VKAs and NOACs.

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

What factors influence a patient’s risk of bleeding on anticoagulation therapy? Join the panel as they discuss the bleeding risks associated with VKAs and NOACs.

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

When to reverse anticoagulation - Part 1

When to reverse and when to wait. Join the panel as they discuss when anticoagulation reversal should be performed.

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

When to reverse and when to wait. Join the panel as they discuss when anticoagulation reversal should be performed.

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

When to reverse anticoagulation - Part 2

The panel discuss the currently available anticoagulation reversal options.

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

The panel discuss the currently available anticoagulation reversal options.

Please note, the slides available for download represent a guide to aid discussion; they are not exhaustive and do not necessarily reflect the opinion of the speakers or of Medthority.com.

Welcome: