Find disease awareness content and relevant supporting materials

The 2026 AHA/ASA guideline for acute ischemic stroke provides updated recommendations on prehospital care, rapid diagnosis, thrombolysis, and endovascular therapy. It introduces expanded eligibility for thrombectomy, supports tenecteplase use, and includes new guidance for paediatric stroke and stroke systems of care.

The 2025 ESO guideline on blood pressure management in acute stroke provides updated recommendations for patients with acute ischaemic stroke and intracerebral haemorrhage. It defines treatment thresholds around reperfusion therapies, advises against routine prehospital BP lowering, and highlights targeted BP control strategies based on stroke subtype and clinical context.

The Australian clinical guideline for diagnosing and managing acute coronary syndromes 2025 provides updated recommendations on ACS diagnosis, high-sensitivity troponin testing, revascularisation strategies, antiplatelet therapy, and secondary prevention. The guidance introduces new myocardial infarction terminology, expanded recognition of coronary occlusion patterns, and revised lipid-lowering and post-discharge care recommendations.

The International Porphyria Network guideline provides evidence-based recommendations for the prevention and management of acute porphyria, including treatment of sporadic and recurrent attacks, long-term follow-up, liver cancer surveillance, and family screening. The guidance aims to standardise care and improve outcomes across diverse healthcare settings.

The Australian evidence-based clinical practice guideline for ADHD provides recommendations on identification, screening, diagnosis, and treatment across children, adolescents, and adults. It supports evidence-based pharmacological and non-pharmacological interventions to improve outcomes and ensure consistent ADHD care.

We also cover a large study that should allay fears of people who should be taking cholesterol-lowering statins. 

The ESO/EANS/ESMINT guideline on aneurysmal subarachnoid haemorrhage provides evidence‑based and consensus recommendations on acute management, aneurysm treatment, and complication prevention. It supports early aneurysm repair, prioritises coiling when appropriate, and emphasises neuro‑ICU care and nimodipine use to improve outcomes.

The ESO guideline on motor rehabilitation provides evidence‑based recommendations to improve recovery after stroke, focusing on therapy intensity, task‑specific training, and functional outcomes. It highlights the importance of increased therapy dose, high‑intensity gait training, and structured rehabilitation approaches to optimise independence and quality of life.

The APASL guideline on acute kidney injury in acute-on-chronic liver failure provides recommendations for the early diagnosis, prevention, and management of AKI in patients with ACLF. The guidance addresses pathophysiology, treatment strategies, and supportive care to improve outcomes in this high-risk population.

The ASH 2026 guideline on the diagnosis of light chain (AL) amyloidosis provides evidence-based recommendations to support timely and accurate diagnosis. The guidance covers laboratory testing, biopsy strategies, and diagnostic pathways to improve early detection and prevent irreversible organ damage.