Oncology is the branch of medicine that deals with the study, diagnosis and treatment of cancer and focuses on the management of cancer from diagnosis through to palliative care.
Cancer is a group of cells (usually derived from a single cell) that has lost its normal control mechanisms. Cancerous cells can develop from any tissue within any organ and can spread throughout the body (metastasise). Cancerous tissue can be divided into those of the blood and blood-forming tissue, and solid tumours, carcinomas or sarcomas, or described as breast cancer including metastatic breast cancer, HER2+, triple negative, gynaecological cancers such as ovarian and cervical, and genitourinary cancer such as prostate cancer.
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Genmab announced very favorable topline results from the Phase II single-arm clinical trial known as innovaTV 204 evaluating tisotumab vedotin administered every three weeks for the treatment of patients who have relapsed or progressed on or after prior treatment for recurrent or metastatic cervical cancer.
The FDA has approved Phesgo (pertuzumab + trastuzumab + hyaluronidase–zzxf), from Genentech/Roche, for injection under the skin to treat adult patients with HER2-positive breast cancer that has spread to other parts of the body, and for treatment of adult patients with early HER2-positive breast cancer.
The Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a marketing authorisation for the medicinal product Aybintio, intended for the treatment of carcinoma of the colon or rectum, breast cancer, non-small cell lung cancer, renal cell cancer, epithelial ovarian, fallopian tube or primary peritoneal cancer, and carcinoma of the cervix.
The pathogenesis of cancer?associated disseminated intravascular coagulation (DIC) is complex and multifactorial. It could present as a spectrum ranging from clinically asymptomatic, but with laboratory markers of coagulation activation...