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Gastroenterology and Hepatology

Containing dedicated Learning Zones, guidelines, trials and news for related conditions in Gastroenterology and Hepatology.

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Last updated: 10th Oct 2022

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Gastroenterology is a branch of medicine that deals with normal function and diseases that affect the digestive tract, from mouth to anus and includes hepatology involving the study of the liver, pancreas, gallbladder and biliary tree.

Featured Learning Zones

Learning Zone

Inflammatory Bowel Disease Learning Zone

Explore our dedicated Learning Zone to find out more about Crohn’s disease and ulcerative colitis, including the epidemiology and immunology of these complex and debilitating diseases.

Learning Zone Homepage

Optimising anti-TNF treatment using biosimilars

Biosimilars are uniquely placed to change clinical practice in the fields of gastroenterology, rheumatology, and dermatology. The adoption of biosimilars can improve patient access to the most appropriate treatment, at the optimum time, to ensure the best possible long-term disease outcomes.

Gastroenterology focuses on the diagnosis and treatment of conditions such gastrointestinal disorders including acute hepatic porphyria, bowel disorders including inflammatory bowel disease, Crohn’s disease, as well as Coeliac disease, hepatitis and pancreatic disorders or transplantation.

Diseases in this section

Bowel Disorders

Containing relevant Learning Zones, guidelines, trials and news.

Gastrointestinal Disorders

Containing relevant Learning Zones, guidelines, trials and news.

Solid Organ Transplantation

Containing relevant Learning Zones, guidelines, trials and news.

Alpha-1 antitrypsin deficiency (AATD) liver disease

Containing relevant Learning Zones, guidelines, trials and news.

Related news and insights

Drug news

Early completion of enrollment in phase II ‘ALTITUDE-NASH’ liver function trial of rencofilstat

Hepion Pharmaceuticals, Inc. focused on Artificial Intelligence (“AI”)-driven therapeutic drug development for the treatment of fibrotic diseases, including non-alcoholic steatohepatitis, hepatocellular carcinoma (“HCC”), and other chronic diseases, announced that it has completed enrollment of 60 NASH stage 3 (“F3”) subjects in the Phase II ALTITUDE-NASH clinical trial

1 mins

Drug news

EU approves Skyrizi for Crohn's disease

AbbVie announced the European Commission (EC) approved Skyrizi (risankizumab, 600 mg intravenous [IV] induction and 360 mg subcutaneous [SC] maintenance therapy) as the first specific interleukin-23 (IL-23) inhibitor for the treatment of adults with moderately to severely active Crohn's disease who have had inadequate response, lost response or were intolerant to conventional or biologic therapy

1 min

Drug news

Phase III KEYNOTE-859 trial met primary endpoint of overall survival in patients with HER2-negative gastric or gastroesophageal junction adenocarcinoma

Merck inc., announced positive topline results from the pivotal Phase III KEYNOTE-859 trial investigating Keytruda Merck’s anti-PD-1 therapy, in combination with chemotherapy for the first-line treatment of patients with human epidermal growth factor receptor 2 (HER2)-negative locally advanced unresectable or metastatic gastric or GEJ adenocarcinoma

1 min

See all news

Related Drugs

Famotidine FAMOTIDINE 40 mg/5mL Navinta LLC

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POTASSIUM CHLORIDE POTASSIUM CHLORIDE 750 mg/1 American Health Packaging

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Dexlansoprazole delayed release DEXLANSOPRAZOLE 60 mg/1 TWI PHARMACEUTICALS, INC.

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Meclizine Hydrochloride MECLIZINE HYDROCHLORIDE 12.5 mg/1 Rising Pharmaceuticals, Inc.

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Lactated Ringers and Dextrose CALCIUM CHLORIDE 20 mg/100mL ICU Medical Inc.

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Sodium Chloride SODIUM CHLORIDE 900 mg/100mL ICU Medical Inc.

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Potassium Chloride Extended-release POTASSIUM CHLORIDE 750 mg/1 NCS HealthCare of KY, LLC dba Vangard Labs

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Ondansetron ODT ONDANSETRON 4 mg/1 Advanced Rx Pharmacy of Tennessee, LLC

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Omeprazole OMEPRAZOLE 20 mg/1 NuCare Pharmaceuticals,Inc.

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Pantoprazole Sodium PANTOPRAZOLE SODIUM 20 mg/1 Aurobindo Pharma Limited

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Related Journals

Journal

Lung and liver transplantation in patients with alpha-1 antitrypsin deficiency

1 mins

Journal

Disease progression in patients with PI*ZZ alpha-1 antitrypsin deficiency

1 mins

Journal

Long term results of liver transplantation for alpha-1 antitrypsin deficiency

1 mins

Journal

Alpha-1 antitrypsin deficiency is under-recognized in individuals with cirrhosis undergoing liver transplantation

1 mins

Journal

Alpha-1 antitrypsin deficiency: A re-surfacing adult liver disorder

1 mins

Journal

Fazirsiran for Liver Disease Associated with Alpha 1-Antitrypsin Deficiency

1 mins

Journal

European Respiratory Society statement: diagnosis and treatment of pulmonary disease in α 1-antitrypsin deficiency

1 mins

Journal

Estimated Prevalence and Number of PiMZ Genotypes of Alpha-1 Antitrypsin in Seventy-Four Countries Worldwide

1 mins

Journal

Clinical considerations in individuals with α 1-antitrypsin PI*SZ genotype

1 mins

Journal

Heterozygosity for the alpha-1-antitrypsin Z allele in cirrhosis is associated with more advanced disease

1 mins

Related Guidelines

Guideline

The Diagnosis and Management of Alpha-1 Antitrypsin Deficiency in the Adult - Alpha-1 Foundation

The Medical and Scientific Advisory Committee of the Alpha-1 Foundation has released new clinical recommendations designed to guide doctors on how to properly diagnose and treat Alpha-1 Antitrypsin Deficiency (Alpha-1) in adults.

1 mins

Guideline

Dietary Therapy and Nutrition Management of Eosinophilic Esophagitis: A Work Group Report of the American Academy of Allergy, Asthma, and Immunology

This work group report addresses the potential challenges of implementing an elimination diet for the management of EoE and provides instructions and tools for physicians, dietitians, and other allied health professionals to help guide them in planning elimination diets for both children and adults.

1 min

Guideline

Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference

We aimed to clarify the use of PPIs in the evaluation and treatment of children and adults with suspected EoE to develop updated international consensus criteria for EoE diagnosis.

1 min

See all guidelines