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Gastroenterology and Hepatology

Containing dedicated Learning Zones, guidelines, trials and news for related conditions in Gastroenterology and Hepatology.

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Last updated: 11th May 2020

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Gastroenterology is a branch of medicine that deals with normal function and diseases that affect the digestive tract, from mouth to anus and includes hepatology involving the study of the liver, pancreas, gallbladder and biliary tree.

Gastroenterology focuses on the diagnosis and treatment of conditions such gastrointestinal disorders including acute hepatic porphyria, bowel disorders including inflammatory bowel disease, Crohn’s disease, as well as Coeliac disease, hepatitis and pancreatic disorders.

Diseases in this section

Bowel Disorders

Containing relevant Learning Zones, guidelines, trials and news.

Gastrointestinal Disorders

Containing relevant Learning Zones, guidelines, trials and news.

Acute Hepatic Porphyria Learning Zone

Acute Hepatic Porphyria (AHP), a subset of porphyria, refers to a family of rare, genetic diseases characterised by potentially life-threatening attacks and, for some patients, chronic manifestations that negatively impact daily functioning and quality of life (QOL).¹ The most common manifestation of attacks is severe, diffuse abdominal pain, although patients can also experience other pain, mood, and gastrointestinal (GI) symptoms.

Learning Zone Homepage

Fluid Management Learning Zone

Welcome to the Fluid Management Learning Zone. In this Learning Zone we provide an overview of fluid management, including albumin for sepsis and septic shock, guidelines for fluid management in liver cirrhosis and fluid management in cardiac surgery.

Learning Zone Homepage

Optimising anti-TNF treatment using biosimilars

Biosimilars are uniquely placed to change clinical practice in the fields of gastroenterology, rheumatology, and dermatology. The adoption of biosimilars can improve patient access to the most appropriate treatment, at the optimum time, to ensure the best possible long-term disease outcomes.

Learning Zone Homepage

Anti-integrins in IBD Learning Zone

The growing understanding of the immunopathogenesis of inflammatory bowel disease (IBD) has provided a variety of novel therapeutic targets. Apart from the tumour necrosis factor-α mediated pathway, which is the target of the first marketed biologics in this indication, several other pathways are involved in triggering an inflammatory response.

Related news and insights

News

Results of phase IIb/III trial of filgotinib in moderately to severely active ulcerative colitis. Gilead Sciences + Galapagos NV

Gilead Sciences, Inc. and Galapagos NV announced positive topline results from SELECTION, a randomized, double-blind, placebo-controlled, Phase IIb/III trial evaluating the efficacy and safety of the investigational, oral, once-daily, selective JAK1 inhibitor filgotinib in 1,348 biologic-naïve or biologic-experienced adult patients with moderately to severely active ulcerative colitis (UC).

3 mins

News

EU approves Entyvio subcutaneous formulation for active ulcerative colitis or Crohn’s disease.- Takeda

Takeda Pharmaceutical announced that the European Commission has granted a Marketing Authorization for the subcutaneous (SC) formulation of Entyvio (vedolizumab), a gut-selective biologic for use as maintenance therapy in adults with moderately to severely active ulcerative colitis (UC) or Crohn’s disease (CD). Entyvio

1 min

Drug news

Health Canada approves Ibsrela to treat irritable bowel syndrome with constipation.- Knight Therapeutics

Knight Therapeutics Inc., has announced that Health Canada has approved Ibsrela (tenapanor) for the treatment of irritable bowel syndrome with constipation (IBS-C) in adults.

1 min

See all news

Related drugs

Zantac 75 Tablets

Spasmonal Forte 120mg hard capsules

Spasmonal 60mg

Senokot Tablets

Senokot Syrup

Scopoderm 1.5 mg Patch

Picolax

Perinal Cutaneous Spray

Percutol Ointment

Pantoloc Control 20mg gastro-resistant tablets

Pancrex V Tablets

Pancrex V Powder

Pancrex V Forte Tablets

Pancrex V Capsules 125mg

Pancrex Granules

Related Guidelines

Guideline

Ulcerative colitis: management

This guideline covers the management of ulcerative colitis in children, young people and adults. It aims to help professionals to provide consistent high-quality care and it highlights the importance of advice and support...

1 mins

Guideline

Transfusion Handbook - 7.3: Transfusion management of major haemorrhage

Early recognition and intervention is essential for survival. The immediate priorities are to control bleeding (surgery and interventional radiology) and maintain vital organ perfusion by transfusing blood and other fluids through...

1 min

Guideline

Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 2: Current Management

The guideline has been condensed into two papers,[...] the second describing current therapeutic management [treatment of active disease and maintenance of medically induced remission].

1 min