Speciality hub

Gastroenterology and Hepatology

Containing dedicated Learning Zones, guidelines, trials and news for related conditions in Gastroenterology and Hepatology.

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Last updated: 11th May 2020

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Gastroenterology is a branch of medicine that deals with normal function and diseases that affect the digestive tract, from mouth to anus and includes hepatology involving the study of the liver, pancreas, gallbladder and biliary tree.

Gastroenterology focuses on the diagnosis and treatment of conditions such gastrointestinal disorders including acute hepatic porphyria, bowel disorders including inflammatory bowel disease, Crohn’s disease, as well as Coeliac disease, hepatitis and pancreatic disorders or transplantation.

Diseases in this section

Bowel Disorders

Containing relevant Learning Zones, guidelines, trials and news.

Gastrointestinal Disorders

Containing relevant Learning Zones, guidelines, trials and news.

Solid Organ Transplantation

Containing relevant Learning Zones, guidelines, trials and news.

Acute Hepatic Porphyria Learning Zone

Acute Hepatic Porphyria (AHP), a subset of porphyria, refers to a family of rare, genetic diseases characterised by potentially life-threatening attacks and, for some patients, chronic manifestations that negatively impact daily functioning and quality of life (QOL).¹ The most common manifestation of attacks is severe, diffuse abdominal pain, although patients can also experience other pain, mood, and gastrointestinal (GI) symptoms.

Learning Zone Homepage

Fluid Management Learning Zone

Welcome to the Fluid Management Learning Zone. In this Learning Zone we provide an overview of fluid management, including albumin for sepsis and septic shock, guidelines for fluid management in liver cirrhosis and fluid management in cardiac surgery.

Learning Zone Homepage

Optimising anti-TNF treatment using biosimilars

Biosimilars are uniquely placed to change clinical practice in the fields of gastroenterology, rheumatology, and dermatology. The adoption of biosimilars can improve patient access to the most appropriate treatment, at the optimum time, to ensure the best possible long-term disease outcomes.

Learning Zone Homepage

Anti-integrins in IBD Learning Zone

The growing understanding of the immunopathogenesis of inflammatory bowel disease (IBD) has provided a variety of novel therapeutic targets. Apart from the tumour necrosis factor-α mediated pathway, which is the target of the first marketed biologics in this indication, several other pathways are involved in triggering an inflammatory response.

Related news and insights

News

Health Canada approves Qinlock for advanced gastrointestinal stromal tumor.- Deciphera Pharma

Deciphera Pharmaceuticals announced that Health Canada has authorized Qinlock (ripretinib), a switch-control tyrosine kinase inhibitor, for sale in Canada for the treatment of adult patients with advanced gastrointestinal stromal tumor (GIST) who have received prior treatment with imatinib, sunitinib, and regorafenib.

1 mins

News

Zeposia met primary and secondary endpoints in TRUE NORTH Phase III study for adult patients with moderate to severe ulcerative colitis.- BMS

Bristol Myers Squibb announced results from True North, a pivotal Phase III trial evaluating oral Zeposia (ozanimod) as an induction and maintenance therapy for adult patients with moderate to severe ulcerative colitis.

1 min

News

CHMP recommends approval of Hepcludex for chronic hepatitis delta virus.- Myr

The Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a conditional marketing authorisation for Hepcludex (bulevirtide), from MYR GmbH, intended for the treatment of chronic hepatitis delta virus (HDV) infection in adult patients with compensated liver disease.

1 min

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Related drugs

Zantac 75 Tablets

Spasmonal Forte 120mg hard capsules

Spasmonal 60mg

Senokot Tablets

Senokot Syrup

Scopoderm 1.5 mg Patch

Picolax

Perinal Cutaneous Spray

Percutol Ointment

Pantoloc Control 20mg gastro-resistant tablets

Pancrex V Tablets

Pancrex V Powder

Pancrex V Forte Tablets

Pancrex V Capsules 125mg

Pancrex Granules

Related Guidelines

Guideline

Guidelines for Hepatitis B & Solid Organ Transplantation

Hepatitis B is a common infectious disease that can result in progressive liver damage requiring liver transplantation. Due to the high prevalence of hepatitis B infection worldwide many patients who are transplanted with other solid organs will...

1 mins

Guideline

Ulcerative colitis: management

This guideline covers the management of ulcerative colitis in children, young people and adults. It aims to help professionals to provide consistent high-quality care and it highlights the importance of advice and support...

1 min

Guideline

Transfusion Handbook - 7.3: Transfusion management of major haemorrhage

Early recognition and intervention is essential for survival. The immediate priorities are to control bleeding (surgery and interventional radiology) and maintain vital organ perfusion by transfusing blood and other fluids through...

1 min

See all guidelines