Myasthenia gravis patient case studies
Experts discuss real-life myasthenia gravis (MG) patient profiles, including challenges and how they were overcome.
Professor Amelia Evoli (Catholic University, Rome, Italy) discusses the outcomes for a man, 53 years of age, diagnosed with MG 5 months after thymectomy. View transcript.
Watch this space for further expert-led MG patient case studies in the coming weeks.
Meet the expert
Professor Amelia Evoli
Amelia Evoli is an Associate Professor of Neurology at the Catholic University, Rome, Italy. Her research interests include MG, Lambert–Eaton myasthenic syndrome, congenital myasthenic syndromes and paraneoplastic neurological diseases.
Disclosures: Alexion, Dianthus, Grifols, and UCB.
Professor Francesco Sacca (University of Naples Federico II, Italy) discusses the journey of a female patient, diagnosed with MG at 79 years of age, with multiple comorbidities. View transcript.
Watch this space for further expert-led MG patient case studies in the coming weeks.
Meet the expert
Professor Francesco Sacca
Francesco Sacca is an Associate Professor of Neurology at the University of Naples Federico II, Italy. His research focuses on MG, multiple sclerosis, ataxias, and migraine. He has been involved in multiple clinical trials focusing on a range of conditions, including MG, multiple sclerosis, neuromyelitis optica, Friedreich ataxia, spinocerebellar ataxia type 2, multiple system atrophy, Parkinson’s disease, and Huntington’s chorea.
Disclosures: Public speaking honoraria from Alexion, argenx, Genpharm, Medison Pharma, Medpharma, and Zai Lab. Compensation for advisory boards or consultation fees from Alexion, argenx, Dianthus Therapeutics, Lexeo Therapeutics, Novartis, and Reata Pharmaceuticals. Principal investigator in clinical trials for Alexion, argenx, Immunovant, Novartis, Prilenia Therapeutics, and Sanofi.
Dr Jennifer Spillane (University College London Hospitals and Guy’s and St Thomas’ NHS Foundation Trust, London, UK) discusses the case of a 38-year-old female diagnosed with MG during the postpartum period, highlighting key considerations for treatment selection and management. View transcript.
Watch this space for further expert-led MG patient case studies in the coming weeks.
Meet the expert
Dr Jennifer Spillane
Jennifer Spillane is a Consultant Neurologist at the National Hospital for Neurology and Neurosurgery, Queen Square, University College London Hospitals and Guy’s and St Thomas’ NHS Foundation Trust in London, UK.
Her research interests include MG and other disorders of the neuromuscular junction, the use of plasma exchange in autoimmune neurological disease, acquired and inherited myopathies, and neurocritical care. Dr Spillane runs the refractory MG clinic at the National Hospital for Neurology and Neurosurgery.
Disclosures: Honoraria for argenx and compensation for advisory boards from argenx and UCB.
Professor Nils Erik Gilhus (University of Bergen, Norway) discusses the case of a 12-year-old boy diagnosed with MG, covering his journey to diagnosis, treatment response, and holistic treatment recommendations, including diet, future work, and physical activity. View transcript.
Watch this space for further expert-led MG patient case studies in the coming weeks.
Meet the expert
Professor Nils Erik Gilhus
Nils Erik Gilhus is Professor of Neurology at the University of Bergen, Norway, and Consultant Neurologist at Haukeland University Hospital. Myasthenia gravis represents his major research topic.
Disclosures: Honoraria from Alexion, Amgen, argenx, Denka, Dianthus Therapeutics, Grifols, Huma, Immunovent, Janssen, Merck, Roche, Takeda, and UCB.
Join Tobias Ruck (BG Universitätsklinikum Bergmannsheil Bochum, Germany) as he shares a case study of a 69-year-old experiencing repeated myasthenic crises. Walk through the patient's journey, from initial diagnosis to severe crisis, and see how evolving treatment approaches are shaping care for people with MG. View transcript.
Meet the expert
Tobias Ruck, MD, MHBA
Tobias Ruck is Director of the Department of Neurology at University Hospital Bergmannsheil in Bochum, Germany. He also leads the Heimer Institute for Muscle Research. His research focuses on immune mechanisms affecting both the central and peripheral nervous systems, with a particular interest in why similar triggers can lead to different clinical outcomes. His team applies advanced techniques – such as flow cytometry, transcriptomics and digital biomarkers – to investigate neuroimmunologic and neuromuscular disorders, including myasthenia gravis.
Disclosures: Honoraria for speaking and travel support from Alexion, argenx, Biogen, Celgene/BMS, Novartis, Roche, Sanofi, and Teva. Participated in advisory board meetings for Alexion, argenx, Biogen, Immunovant, J&J, Merck, Roche, Sanofi, and UCB. Research funding from Alexion, argenx, Biogen, Merck, Novartis, Roche, Sanofi, and SERB Pharmaceuticals.
This content has been developed independently by Medthority who previously received educational funding from argenx in order to help provide its healthcare professional members with access to the highest quality medical and scientific information, education and associated relevant content.