Rheumatology is branch of medicine that deals with the diagnosis and treatment of disorders of connective tissues and joints, many of which are now known to be immune mediated conditions.
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Rheumatic diseases can be caused by trauma, heredity, genetic abnormality, autoimmune disease, or another underlying condition such as cancer. There are more than 150 different types of rheumatic disorders, including arthritis, rheumatoid and osteoarthritis, gout and lupus.
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Pfizer announced co-primary endpoint results from a recently completed post-marketing required safety study, ORAL Surveillance (A3921133; NCT02092467) of Xeljanz (tofacitinib) in rheumatoid arthritis (RA).
AbbVie announced that the European Commission (EC) has approved Rinvoq (upadacitinib?, 15 mg), an oral, once daily selective and reversible JAK inhibitor for the treatment of adults with active psoriatic arthritis (PsA) and active ankylosing spondylitis (AS).
AbbVie announced positive top-line results from two Phase III studies in adults with active psoriatic arthritis, KEEPsAKE-1 and KEEPsAKE-2 , showing that significantly more patients treated with risankizumab (150 mg) achieved the primary endpoint of ACR20 response at week 24 versus placebo.