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Insight

Challenges in transplant organ rejection

Read time: 5 mins
Last updated:10th Aug 2020
Published:10th Aug 2020
Since the first successful organ transplant procedures in the 1950s, immunosuppressive agents have played a key role by reducing grafted organ rejection and improving patient survival. In this series of articles, we’ll give updates on the various existing treatments as well as on the horizon for transplant organ rejection.
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References

  1. Claeys E, Vermeire K, Leuven KU. Immunosuppressive drugs in organ transplantation to prevent allograft rejection: Mode of action and side effects. J Immunol Sci. 2019;3(4):14–21.
  2. Daniel Abramowicz, Oberbauer R, Heemann U, Viklicky O, Peruzzi L, Mariat C, et al. Recent advances in kidney transplantation: a viewpoint from the Descartes advisory board. Nephrol Dial Transpl. 2018;33(10):1699–1707.
  3. Saldanha IJ, Akinyede O, Robinson KA. Immunosuppressive drug therapy for preventing rejection following lung transplantation in cystic fibrosis. Cochrane Database Syst Rev. 2018;6(6). doi:10.1002/14651858.CD009421.pub4.
  4. Benvenuto LJ, Anderson MR, Arcasoy SM. New frontiers in immunosuppression. J Thorac Dis. 2018;10(5):3141–3155.