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Abraxane (Celgene) success in Phase III study of Pancreatic Cancer

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Last updated:11th Nov 2012
Published:11th Nov 2012
Source: Pharmawand

In a Phase III study,(the MPACT (Metastatic Pancreatic Adenocarcinoma Clinical Trial), Abraxane (paclitaxel protein-bound particles for injectable suspension) (albumin-bound),from Celgene, in combination with gemcitabine in treatment-na�ve patients with advanced Pancreatic Cancer met its primary endpoint of overall survival. In the study, Abraxane in combination with gemcitabine demonstrated a statistically significant improvement in overall survival compared to patients receiving gemcitabine alone.

A late-breaker placeholder abstract for this study has been submitted to the American Society of Clinical Oncology�s (ASCO) 2013 Gastrointestinal Cancers Symposium being held in San Francisco on January 24-26, 2013.

Based on the results of the MPACT study, the company plans to submit dossiers for registration in the US, Europe and other markets.

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