Barriers to uptake of clinical practice guidelines for mCRPC
Axel Merseburger discusses some key challenges in following clinical practice guideline recommendations for mCRPC management, and why guideline uptake remains low. View transcript.
Axel Merseburger, MD, PhD
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So the question is, what are the clinical barriers to uptake of clinical practice guidelines for mCRPC? And it is really, really depending on the patient profile, and also on novel developments we have. And guidelines are only as fast as the guidelines panel will take those changes in the scientific world, and what we learn from publications from recent approvals into their recommendations. So, sometimes an approval of another substance is much faster than the guidelines recommendations.
So, this is something what we need to keep in mind, and that's why we need to inform ourself, and all, let's say, channels we can use like from the internet, from PubMed, from society recommendation, and surely the updates from the guidelines. And also, let me give you an example.
The patients that undergo genetic testing which is recommended in those modern guidelines, it's not always so easy to do this because of rural areas, because of long travel distances, because of the pandemic situation we have had the last couple years. So, a lot of aspects that play an important role in our clinical decision-making, and why we might have barriers in those guidelines for treating men with mCRPC. And hopefully in the future, modern developments, or approval of substances, and combinations deliver easier options for all patients.
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