Pathophysiology
Pathophysiology of Atopic Dermatitis
Atopic dermatitis (AD) is an intensely pruritic chronic skin disease caused by underlying type 2 inflammation. It is characterized as having a multifactorial pathophysiology involving dysregulation of the type 2 immune pathway and influenced by environmental and genetic factors.1,2
Watch this video, with Dr Alan Irvine, to understand how AD is a complex multifactorial inflammatory disease.
- Atopic Dermatitis is a Multifactorial Disease (00:13)
Alan Irvine, WCPD 2021 - Characteristics of Type 2 Inflammation (01:05)
Alan Irvine, WCPD 2021 - Mechanism of Skin Barrier Disruption (3:10)
Alan Irvine, WCPD 2021 - Systemic Influence of Type 2 Inflammation (04:51)
Alan Irvine, WCPD 2021 - Progression of Atopic Dermatitis (5:31)
Alan Irvine, WCPD 2021
References
- Beck LA, et al. JID Innov. 2022;2(5):100131.
- Haddad EB, et al. Dermatol Ther (Heidelb). 2022;12(7):1501-1533.
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