Congress highlights
In this section
ASN 2022 congress highlights
Join Dr Carla Nester as she discusses numerous findings presented at the American Society of Nephrology (ASN) 2022 Congress, which was held in November in Orlando. Dr Nester provides a comprehensive overview of the presentations, which included data on new treatment targets, the latest findings on nephritic factors and novel treatments for C3 glomerulopathy (C3G) and other complement-mediated kidney diseases (CMKDs).
Complement is known to play a role in several kidney diseases. Here, Dr Carla Nester, Director of Paediatric Nephrology, Dialysis and Transplantation at the Stead Family Children’s Hospital, University of Iowa, describes the emergence of complement inhibitors as a potential therapeutic approach for such diseases. She also discusses research into related conditions presented at the ASN 2022 Congress.
Related content from ASN 2022
- Md Dom et al. evaluated the associations of complement proteins and early diabetic kidney disease in type 1 diabetes
- Bruno et al. described the effects of complement activation in podocyte structure and function in membranous nephropathy
- Li et al. presented data showing a correlation between urine C5b-9 and the activity index and between the Ba level and the chronicity index in lupus nephritis
- Several proteomic studies depicted the role of complement in glomerulonephritis in general (from microdissection), with one study suggesting that this may be a way to differentiate between post-infectious glomerulonephritis and C3G; see poster by Palma et al. for more
- Tampe et al. presented the role of intrarenal synthesis of complement and how it may correlate with decline in kidney function in antineutrophil cytoplasmic antibody (ANCA)-associated renal vasculitis
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This content has been developed independently of the sponsor, Novartis Pharma AG, who has reviewed the content for scientific/medical accuracy. Medthority received educational funding from the sponsor in order to help provide its healthcare professional members with access to the highest quality medical and scientific information, education and associated relevant content. This Learning Zone has been developed by EPG Health, with key insights and expert review from Dr Carla Nester and Dr Edwin Wong.