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Journal

Novel Therapies for Treatment of Food Allergy

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Published:31st Jan 2020
Author: Albuhairi S, Rachid R.
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Ref.:Immunol Allergy Clin North Am. 2020 Feb;40(1):175-186.
DOI:10.1016/j.iac.2019.09.007
Novel Therapies for Treatment of Food Allergy


Food allergy prevalence has increased over the past 2 decades and is estimated to affect 8% of children and 4% to 10% of adults. There is an unmet need to evaluate new therapeutic modalities that may decrease the risk of food-induced anaphylaxis and improve patients' quality of life. Oral, epicutaneous, and sublingual food immunotherapies have different safety and efficacy profiles, and their long-term outcome and applicability are unclear. Food allergy trials are currently evaluating different biologics (given as monotherapy or adjunct to immunotherapy), modified food proteins, DNA vaccines, and fecal microbiota transplantation.


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