These guidelines (July 2015) reflect changes in treatments, since the 2010 Interim RVO Guidelines. The guidelines provide evidence-based, clinical advice for the management of different aspects of RVO. The scope is limited to current diagnostic tools, management and service set-up and delivery to facilitate delivery of optimal care. They are aimed primarily at ophthalmologists but are relevant to other healthcare professionals, service providers, and commissioning organisations as well as patient groups. It is hoped that, if used appropriately, the guidelines will lead to a uniformly high standard of management of patients with RVO.