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Food Allergy Learning Zone
Declaration of sponsorship Novartis Pharma AG

Diagnosing food allergy

Declaration of sponsorship Novartis Pharma AG
Read time: 45 mins
Last updated:4th Aug 2021
Published:4th Aug 2021

Learn about the pathophysiology of IgE-mediated food allergy and the tests used to support its diagnosis. Discover:

  • Mechanisms of oral tolerance and sensitisation in our infographic
  • The diagnostic pathway of food allergy in our interview with Dr Alexandra Santos
  • A summary of diagnostic tests in our underlying mechanisms of sensitisation diagram

Pathophysiology of food allergy

Both oral tolerance and sensitisation can be promoted by five key components of the immune system: the epithelium, innate immune cells, T cells, B cells, and effector cells1.

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Diagnostic pathway for food allergy

The precise diagnosis of food allergy is essential for guiding safe and suitably restrictive dietary management, while minimising the impact on a patients’ quality of life6,7

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Diagnostic tests for IgE-mediated food allergy

 

Following the collection and interpretation of a clinical history, when IgE-mediated food allergy is suspected, further evidence of sensitisation can then be obtained through appropriately selected diagnostic tests9,10.

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References

  1. Anvari S, Miller J, Yeh CY, Davis CM. IgE-Mediated Food Allergy. Clin Rev Allergy Immunol. 2019;57(2):244–260.
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