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Dexamethasone 2mg Tablets

Read time: 17 mins
Last updated: 25 Sep 2020
Published: 25 Sep 2020

4.1 Therapeutic indications

Dexamethasone is indicated as a treatment for certain endocrine and non-endocrine disorders, in certain cases of cerebral oedema, and for diagnostic testing of adrenocortical hyperfunction.

Endocrine disorders: Primary or secondary adrenocortical insufficiency, congenital adrenal hyperplasia.

Non-endocrine disorders: Dexamethasone may be used in the treatment of non-endocrine corticosteroid responsive conditions, including:

Allergy and anaphylaxis: Angioneurotic oedema, anaphylaxis.

Arteritis collagenosis: Polymyalgia rheumatica, polyarteritis nodosa.

Blood disorders: Haemolytic anaemia, leukaemia, myeloma.

Cardiovascular disorders: Post-myocardial infarction syndrome.

Gastro-intestinal: Crohn's disease, ulcerative colitis.

Hypercalcaemia: Sarcoidosis.

Infections (with appropriate chemotherapy): Miliary tuberculosis.

Muscular disorders: Polymyositis.

Neurological disorders: Raised intra-cranial pressure secondary to cerebral tumours.

Ocular disorders: Anterior and posterior uveitis, optic neuritis.

Renal disorders: Lupus nephritis.

Respiratory disease: Bronchial asthma, aspiration pneumonitis.

Rheumatic disorders: Rheumatoid arthritis.

Skin disorders: Pemphigus vulgaris.

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Drugs appearing in this section are approved by UK Medicines & Healthcare Products Regulatory Agency (MHRA), & the European Medicines Agency (EMA).