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Clinical trial

Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)

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Last updated:10th Jul 2013
Identifier: NCT01897532

The aim of the study is to investigate the longterm impact on cardiovascular morbidity, mortality and renal function of treatment with linagliptin in a selected population of patients with T2DM and to compare outcomes against placebo, on a background of standard of care.


Study Type: Interventional  (Clinical Trial)
Actual Enrollment: 7003 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Treatment
Official Title: CARMELINA: A Multicenter, International, Randomized, Parallel Group, Double-blind, Placebo-controlled, Cardiovascular Safety and Renal Microvascular Outcome Study With Linagliptin, 5 mg Once Daily in Patients With Type 2 Diabetes Mellitus at High Vascular Risk
Actual Study Start Date: July 10, 2013
Actual Primary Completion Date: December 22, 2017
Actual Study Completion Date: January 18, 2018

Arm:
- Experimental:
Linagliptin
- Placebo Comparator: Placebo

Category Value
Date last updated at source 2018-02-12
Study type(s) Interventional
Expected enrolment 7003
Study start date 2013-07-10
Estimated primary completion date 2017-12-22

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