Pilot Study of the Effect of Liraglutide on Weight Loss and Gastric Functions in Obesity

Obesity is associated with differences in stomach function, feeling of fullness after meals, and total calories consumed at a buffet meal. Based upon previous research, our study hypothesis is that weight loss with pharmacological agents may be individualized, based on the abnormality in those gastrointestinal functions. These studies will provide support for the principle that specific obesity medications should be selected according to individual characteristics, and it is anticipated that this approach will enhance efficacy of medication treatment of obesity.


Study Type: Interventional
Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Factorial Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Treatment
Official Title: Pilot Study of the Effect of Liraglutide on Weight Loss and Gastric Functions in Obesity
Estimated Enrollment: 40
Study Start Date: December 2015
Estimated Study Completion Date: December 2016
Estimated Primary Completion Date: December 2016 (Final data collection date for primary outcome measure)

Arms:
- Active Comparator: Liraglutide
- Placebo Comparator: placebo