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Clinical trial

A trial of AK112 (PD1/VEGF bispecific) in combination with chemotherapy in patients with NSCLC

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Last updated: 17th Sep 2026
Status: Active, not recruiting
Identifier: NCT04736823
A trial of AK112 (PD1/VEGF bispecific) in combination with chemotherapy in patients with NSCLC

 

Trial Fact Box
NCT Code NCT04736823
Sponsor Akeso
Study type(s) Interventional
Phase Phase 2
Enrollment (Actual) 265
Study Start (Actual) 01 February 2021
Primary Completion (Estimated) July 2026
Study Completion (Estimated) December 2026

Official Title:
A Phase II Trial of AK112 (PD1/VEGF Bispecific) in Combination With Chemotherapy in Patients With NSCLC

Brief Summary: 
This is a phase II study. All patients are stage IIIB/C or IV non-small cell lung cancer(NSCLC), Eastern Cooperative Oncology Group (ECOG) performance status 0-1. The purpose of this study is to evaluate the efficacy and safety of AK112 in combination with chemotherapy in patients with NSCLC.


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