This meta-analysis compared inhaled vs systemic corticosteroids for COPD exacerbations. It included 20 RCTs with 2140 participants. No significant differences were found in treatment failure rate, breathlessness, or serious adverse events. Fewer adverse events were noted with inhaled corticosteroids. More research is needed to confirm these findings.
This meta-analysis delves into the role of mucolytics as an add-on treatment for COPD exacerbations. It highlights the potential benefits of mucolytics in increasing treatment success rate and improving symptom scores, despite some methodological concerns. The study calls for further rigorous RCTs for validation.
Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in children and is associated with significant risk of educational failure, interpersonal problems, mental illness, and delinquency.
This British Association for Psychopharmacology guideline replaces the original version published in 2010, and contains updated information and recommendations.
We conducted a systematic review and meta-analysis to access HPV vaccines' safety and immunogenicity in Systemic Lupus Erythematosus (SLE) women.
Objective: To compare and contrast the efficacy and safety of patiromer and sodium zirconium cyclosilicate (ZS-9) in the treatment of hyperkalemia.
The objective of this systematic review and meta-analysis was to compare the safety and efficacy of NSAIDs with opioids and paracetamol (acetaminophen) for the management of acute renal colic.
Objective: To evaluate the effectiveness of preventive psychological and/or educational interventions for anxiety in varied population types.
Inflammatory illness is associated with depression. Preclinical work has shown that chemokines are linked with peripheral-central crosstalk and may be important in mediating depressive behaviours.
Chronic obstructive pulmonary disease (COPD) patient care must include confirming a diagnosis with postbronchodilator spirometry. The evidence from this systematic review and meta-analysis leads to the recommendation that all symptomatic patients with spirometry-confirmed COPD should receive long-acting bronchodilator maintenance therapy.