Simlandi (adalimumab-ryvk) is available in the USA as an interchangeable biosimilar to Humira. Teva + Alvotech
Teva Pharmaceuticals, a U.S. affiliate of Teva Pharmaceutical Industries Ltd and Alvotech announced the availability of Simlandi (adalimumab-ryvk) injection in the U.S., as an interchangeable biosimilar to Humira for the treatment of adult rheumatoid arthritis, juvenile idiopathic arthritis, adult psoriatic arthritis, adult ankylosing spondylitis, Crohn’s disease, adult ulcerative colitis, adult plaque psoriasis, adult hidradenitis suppurativa and adult uveitis
Simlandi is approved by the FDA as the first high-concentration, citrate-free biosimilar to Humira with interchangeability exclusivity for the 40mg/0.4mL injection. While both low-concentration and high-concentration strength biosimilars of Humira are marketed in the U.S. today, nearly 88 percent of U.S. prescriptions for adalimumab are for the high-concentration presentation.