This site is intended for healthcare professionals
Blue test tubes arranged in a line, disappearing into the background
  • Home
  • /
  • News
  • /
  • 2021
  • /
  • 6
  • /
  • Health Canada approves Abecma for multiple myeloma...
News

Health Canada approves Abecma for multiple myeloma.- BMS

Read time: 1 mins
Published:1st Jun 2021
"
Bristol Myers Squibb Canada announced Health Canada has granted conditional approval (NOC/c) for Abecma (idecabtagene vicleucel; ide-cel) as the first and only B-cell maturation antigen (BCMA)-directed chimeric antigen receptor (CAR) T cell immunotherapy for adults with multiple myeloma (MM). Abecma is indicated for MM patients who have received at least three prior therapies, including an immunomodulatory agent, a proteasome inhibitor, and an anti-CD38 antibody and who are refractory to their last treatment.

This conditional approval is based on the results of the pivotal Phase II KarMMa study which demonstrated Abecma's ability to deliver rapid, deep and durable responses with a single infusion.Comment: Abecma, a CAR T therapy, uses patients' T cells to create a personalized version of their own immune system, potentially improving the chances of anti-tumour response long after treatment administration. As an anti-BCMA CAR T cell therapy, Abecma recognizes and binds to BCMA, a protein that is nearly universally expressed on cancer cells in MM, leading to the death of BCMA-expressing cells.

Condition: Multiple Myeloma
Type: drug

Learning Zones

The Learning Zones are an educational resource for healthcare professionals that provide medical information on the epidemiology, pathophysiology and burden of disease, as well as diagnostic techniques and treatment regimens.

Related news and insights