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Takeda provides update on TOURMALINE-MM2 phase III trial of ixazomib + lenalidomide + dexamethasone to treat transplantation ineligible multiple myeloma patients.

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Published:11th Mar 2020
Takeda Pharmaceutical Company Limited announced the results from the TOURMALINE-MM2 study designed to evaluate the addition of Ninlaro (ixazomib) to lenalidomide and dexamethasone in newly diagnosed transplant ineligible multiple myeloma patients. The addition of ixazomib to lenalidomide and dexamethasone resulted in an improvement in median progression-free survival (PFS) of 13.5 months (35.3 months versus 21.8 months; hazard ratio [HR] 0.83; p=0.073); however, it did not meet the threshold for statistical significance. The safety profile associated with Ninlaro from the TOURMALINE-MM2 trial was generally consistent with the existing prescribing information. Results from the TOURMALINE-MM2 study will be submitted to an upcoming medical congress.
Condition: Multiple Myeloma
Type: drug

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