NICE does not recommend Opdivo (nivolumab) as a treatment for squamous NSCLC- BMS
The National Institute for Health and Care Excellence (NICE) in draft guidance has not recommended Opdivo (nivolumab) from BMS as a cost effective treatment for adult patients with locally advanced squamous NSCLC whose disease has progressed after prior chemotherapy. This rejection was made despite an offer of discount by BMS. Opdivo had shown in the CHECKMATE- 017 trial that 42% of patients with advanced squamous NSCLC were still alive at one year compared to 24% of those treated with docetaxel. The guidance is now for consultation.
Related news and insights
Regeneron Pharmaceuticals, Inc. announced the FDA as accepted for review the Eylea (aflibercept) Injection supplemental Biologics License Application (sBLA) for an every 16-week 2 mg dosing regimen (after initial monthly doses) in patients with diabetic retinopathy (DR). The target action date for the FDA decision is February 28, 2023.
VBI Vaccines Inc. a biopharmaceutical company driven by immunology in the pursuit of powerful prevention and treatment of disease, announced that new data from a follow-up analysis of a subset of participants from the pivotal Phase III study (PROTECT) of the Company’s 3-antigen prophylactic hepatitis B (HBV) vaccine, were presented in an oral presentation at The International Liver Congress 2022 (ILC), the Annual Meeting of the European Association for the Study of the Liver (EASL), which took place on June 26, 2022.