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FDA approves Avastin for treatment of Ovarian Cancer - Genentech/Roche

Read time: 1 mins
Last updated:15th Nov 2014
Published:15th Nov 2014
Source: Pharmawand

Genentech has announced that the FDA approved Avastin on 14 November 2014, in combination with chemotherapy for the treatment of women with platinum-resistant, recurrent Ovarian Cancer. The approval was based on results from the Phase III AURELIA study that showed Avastin plus chemotherapy reduced the risk of disease worsening or death (progression-free survival or PFS) by 62 per-cent compared to women who received chemotherapy alone (median PFS: 6.8 vs. 3.4 months, Hazard Ratio (HR)=0.38; p<0.0001). Adverse events were consistent with those seen in previous trials of Avastin across tumour types for approved indications, but also included high blood pressure and pain, redness or swelling of the hands or feet from the Phase III study.

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