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NICE draft guidance on Sovaldi for Hepatitis C - Gilead Sciences.

Read time: 1 mins
Last updated:15th Aug 2014
Published:15th Aug 2014
Source: Pharmawand

NICE in draft guidance now states that it is now planning to recommend the Solaldi (sofosbuvir) from Gilead Sciences, in combination with peginterferon alfa and ribavirin for treating: genotype 1 chronic Hepatitis C in adults; genotype 3 chronic Hepatitis C in adults with cirrhosis; and genotype 3 chronic Hepatitis C in adults without cirrhosis only if they have had treatment for hepatitis C before. It does not recommend Sovaldi in combination with peginterferon alfa and ribavirin for treating genotype 4, 5 and 6 chronic Hepatitis C in adults.

In combination with ribavirin alone, NICE plans to recommend�s Sovaldi�s use as an option for treating: genotype 2 chronic Hepatitis C in adults, only if they have had treatment for chronic Hepatitis C before and are intolerant to or ineligible for interferon therapy, or if they have had treatment for chronic Hepatitis C before, regardless of interferon eligibility; and for treating genotype 3 chronic Hepatitis C only in adults with cirrhosis. It does not plan to recommend Sovaldi, in combination with ribavirin alone, for treating adults with genotype 1,4, 5 and 6 chronic Hepatitis C.

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