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NEJM study shows Votrient's benefits in Kidney Cancer

Read time: 1 mins
Last updated:25th Aug 2013
Published:25th Aug 2013
Source: Pharmawand

Results from a Phase III trial of 1,100 metastatic Kidney Cancer patients comparing Votrient (pazopanib), from Glaxo Smith Kline, with Sutent (sunitinib), are published in the August 22 issue of the New England Journal of Medicine. Median time before the cancer progressed was similar: 8.4 months for Votrient and 9.5 months for sunitinib. Median overall survival was also comparable: 28.4 months for Votrient vs 29.3 months for sunitinib.

However Votrient was rated superior on 11 or 14 measures of quality of life. In addition, Votrient patients had fewer phone consultations with doctors and visited ER less frequently. See: "Pazopanib versus Sunitinib in Metastatic Renal-Cell Carcinoma" Robert J. Motzer et al. N Engl J Med 2013, 369, 722-31. DOI: 10.1056/NEJMoa1303989

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