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Immunopathogenesis, Diagnosis, and Treatment of Multiple Sclerosis: A Clinical Update

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Published:1st Feb 2023
Author: Pérez CA, Cuascut FX, Hutton GJ.
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Ref.:Neurol Clin. 2023 Feb;41(1):87-106.
DOI:10.1016/j.ncl.2022.05.004
Immunopathogenesis, Diagnosis, and Treatment of Multiple Sclerosis: A Clinical Update


Multiple sclerosis (MS) is the most prevalent nontraumatic disabling neurologic condition among young adults worldwide. The diagnosis and management of MS is complex. The goal of this review is to provide an updated and practical approach to the diagnosis and treatment approaches in MS, emphasizing current understanding of immunopathogenesis, recent advances, and future directions, for both MS and non-MS clinicians.


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