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Epigenetics in age-related macular degeneration: new discoveries and future perspectives

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Published:1st Mar 2020
Author: Gemenetzi M, Lotery AJ.
Availability: Free full text
Ref.:Cell Mol Life Sci. 2020 Mar;77(5):807-818.
DOI:10.1007/s00018-019-03421-w
Epigenetics in age-related macular degeneration: new discoveries and future perspectives


The study of epigenetics has explained some of the 'missing heritability' of age-related macular degeneration (AMD). The epigenome also provides a substantial contribution to the organisation of the functional retina. There is emerging evidence of specific epigenetic mechanisms associated with AMD. This 'AMD epigenome' may offer the chance to develop novel AMD treatments.


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