Journal

Epigenetics in age-related macular degeneration: new discoveries and future perspectives

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Published:1st Mar 2020

Author: Gemenetzi M, Lotery AJ.

Source: Cellular and Molecular Life Sciences

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Ref.:Cell Mol Life Sci. 2020 Mar;77(5):807-818.

DOI:10.1007/s00018-019-03421-w

Epigenetics in age-related macular degeneration: new discoveries and future perspectives

The study of epigenetics has explained some of the 'missing heritability' of age-related macular degeneration (AMD). The epigenome also provides a substantial contribution to the organisation of the functional retina. There is emerging evidence of specific epigenetic mechanisms associated with AMD. This 'AMD epigenome' may offer the chance to develop novel AMD treatments.

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