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Responsive Neurostimulation for the Treatment of Epilepsy.

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Published:1st Apr 2019
Author: Matias CM, Sharan A, Wu C.
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Ref.:Neurosurg Clin N Am. 2019;30(2):231-242.

There are a significant number of patients with epilepsy who are drug-resistant and for whom resective procedures are not an option. For these patients, neuromodulation may be an option, including closed-loop stimulation, such as responsive neurostimulation (RNS). The RNS System is a programmable and responsive device that consists of leads, a pulse generator, and an external programmer. An algorithm detects specific patterns of epileptogenic activity and triggers focal stimulation to interrupt a seizure. RNS is an effective and safe adjunctive therapy that in addition to seizure frequency reduction may have other applications, such as drug-response evaluation and long-term electrocorticography recording.


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