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Mechanisms of Disease of Eosinophilic Esophagitis

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Published:22nd May 2016
Author: Davis BP, Rothenberg ME.
Availability: Free full text
Ref.:Annu Rev Pathol. 2016 May 23;11:365-93.
DOI:10.1146/annurev-pathol-012615-044241
Mechanisms of Disease of Eosinophilic Esophagitis


Eosinophilic esophagitis (EoE) is a recently recognized inflammatory disease of the esophagus with clinical symptoms derived from esophageal dysfunction. The etiology of EoE is now being elucidated, and food hypersensitivity is emerging as the central cornerstone of disease pathogenesis. Herein, we present a thorough picture of the current clinical, pathologic, and molecular understanding of the disease with a focus on disease mechanisms.


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