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Guideline

Gastric and oesophageal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

Read time: 1 mins
Last updated: 15th Oct 2026
Availability: Free full text
Status: Current
Gastric and oesophageal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up - European Society for Medical Oncology (ESMO)


• This ESMO CPG provides key recommendations and algorithms for managing both gastric and oesophageal cancer.

• It covers the full patient journey: diagnostic work-up, staging, risk stratification, treatment, follow-up, surveillance.

• Diagnostic work-up recommendations include endoscopy, histopathology, biomarker testing (e.g. HER2, MSI, CLDN18.2, PD-L1).

• Treatment recommendations are tailored according to disease stage, prior therapy and patient biomarker profiles.

• All recommendations are based on current evidence, complemented by expert consensus where high-level evidence is limited.


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