GSK announced that it has submitted a regulatory application to the European Medicines Agency (EMA) for its malaria vaccine candidate,...
The world's first malaria vaccine, RTS,S (Mosquirix) developed by GlaxoSmithKline, provides some protection after three doses but its effect declines...
The effectiveness of a Malaria Vaccine, RTS,S, developed by GlaxoSmithKline wanes over time, with the shot protecting only 16.8 percent...
Final results from a large-scale Phase III trial of RTS,S malaria vaccine candidate, from Glaxo Smith Kline, including the impact...
GSK plc and Medicines for Malaria Venture (MMV) announced that the World Health Organization (WHO) has awarded prequalification to tafenoquine, the first single-dose medicine for the prevention of relapse of Plasmodium vivax (P. vivax) malaria
Novartis and Medicines for Malaria Venture (MMV) announce positive data from their phase II/III CALINA study, demonstrating that a novel formulation of Coartem (artemether-lumefantrine) developed for babies weighing less than 5kg with malaria has the required pharmacokinetic profile and good efficacy and safety
In this Review, we explore the challenges in assessing the efficacy of candidate SARS-CoV-2 vaccines, discuss the caveats needed to interpret reported efficacy endpoints, and provide insight into answering the seemingly simple question, “Does this COVID-19 vaccine work?”
The World Health Organization (WHO) announced its recommendation of the R21/Matrix-M malaria vaccine to prevent malaria in children following advice from its Strategic Advisory Group of Experts (SAGE) and Malaria Policy Advisory Group (MPAG)
Areas covered: We provide an overview of the molecular pathology that leads to an increase in Aβ peptide accumulation, of the mechanism of action for antibody mediated therapies and of the therapeutic vaccines that target...
Results from a pivotal, large-scale Phase III trial, published online in the New England Journal of Medicine, show that the...