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This multicentre audit reviewed the records of 431 patients who had undergone major elective surgery. The authors sought to determine how well IV fluids were prescribed both intraoperatively and perioperatively when compared with current guidance.

We assessed whether perioperative fluid management with balanced solutions and a limited volume of hydroxyethyl starch (renal-protective fluid management [RPF] strategy) could improve renal outcomes after cardiovascular surgery.

Intravenous (IV) fluids may be associated with complications not often attributed to fluid type. Fluids with high chloride concentrations such as 0.9 % saline have been associated with adverse outcomes in surgery and critical care.

This NICE guideline outlines principles for prescribing and managing intravenous fluid therapy in children and young people under 16. It emphasizes assessing fluid and electrolyte status and using isotonic crystalloids for routine maintenance, aiming to improve safety across hospital settings.

Guidelines to promote the early recovery of patients undergoing major surgery recommend a restrictive intravenous-fluid strategy for abdominal surgery. However, the supporting evidence is limited, and there is concern about impaired organ perfusion.

Nuwellis, Inc. a commercial-stage company focused on transforming the lives of people with fluid overload, announced the publication of key clinical data supporting the use of ultrafiltration with the Aquadex FlexFlow System in high-risk postoperative coronary artery bypass grafting (CABG) patients in the Journal of Cardiac Surgery

Introduction: Extracellular tau is hypothesized to mediate the onset and progression of tauopathies, including Alzheimer's disease, progressive supranuclear palsy, and a subset of frontotemporal lobar degenerations.

In 2007, the Saline versus Albumin Fluid Evaluation-Translation of Research Into Practice Study (SAFE-TRIPS) reported that...

In this post-hoc, subgroup analysis and prospective, single-centre nested cohort from the SPLIT trial, the investigators hypothesised that patients receiving Plasma-Lyte 148 would require fewer blood products and have less post-operative bleeding than those receiving saline.

This study explored fluid prescribing practices in intensive care, providing a picture of how fluid resuscitation is being managed internationally.