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    Blue test tubes arranged in a line, disappearing into the background
    Drug news
    27/02/18

    REVA Medical, Inc.has announced CE Mark of the 2.5 millimeter diameter size and the first implant of the Fantom Encore bioresorbable scaffold.

    REVA Medical, Inc. a leader in bioresorbable polymer technologies for vascular applications, announced CE Mark of the 2.5 millimeter diameter...

    Journals
    Journal
    01/03/18

    Review of oritavancin for the treatment of acute bacterial skin and skin structure infections

    Objective: To assess critically oritavancin, a second-generation lipoglycopeptide, for the treatment of Acute Bacterial Skin and Skin Structure Infections caused by susceptible Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus.

    • Source: Farmacia Hospitalaria
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    Drug news
    25/02/18

    Wave Life Sciences and Takeda collaborate on nucleic acid therapies for CNS disorders including WVE 120102 for Huntington disease.

    Wave Life Sciences Ltd. , a biotechnology company focused on delivering transformational therapies for patients with serious, genetically-defined diseases, announced...

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    Clinical trial
    01/03/22

    Macular Pigment and Visual Performance in Glaucoma Patients

    The purpose of this study is to determine cross-sectional relationships between macular pigment optical density (MPOD) and visual performance in glaucoma

    • Source: ClinicalTrials.gov
    Journals
    Journal
    01/03/22

    Prediction of the Risk of Alopecia Areata Progressing to Alopecia Totalis and Alopecia Universalis: Biomarker Development with Bioinformatics Analysis and Machine Learning

    Background: Alopecia areata (AA) is an autoimmune disease typified by nonscarring hair loss with a variable clinical course. Although there is an increased understanding of AA pathogenesis and progress in its treatments, the outcome of AA patients remains unfavorable, especially when they are progressing to the subtypes of alopecia totalis (AT) or alopecia universalis (AU).

    • Source: Dermatology
    Journals
    Journal
    01/03/19

    Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

    Risk for late-onset Alzheimer's disease (LOAD), the most prevalent dementia, is partially driven by genetics. To identify LOAD risk loci, we performed a large genome-wide association meta-analysis of clinically diagnosed LOAD (94,437 individuals).

    • Source: Nature Genetics
    Journals
    Journal
    31/08/17

    Population Pharmacokinetics and Immunogenicity of Adalimumab in Adult Patients with Moderate-to-Severe Hidradenitis Suppurativa

    Introduction: Hidradenitis suppurativa (HS) is a serious, debilitating, chronic inflammatory skin disease. Adalimumab is a fully human, immunoglobulin G1 monoclonal antibody specific for tumor necrosis factor-alpha...

    • Source: Clinical Pharmacokinetics
    Journals
    Journal
    07/02/17

    Analysis of the association of chronic spontaneous urticaria with interlekin-4, -10, transforming growth factor-β1, interferon-γ, interleukin-17A and -23 by autologous serum skin test

    To contribute to the understanding of the pathogenesis of chronic spontaneous urticaria (CSU) by identifying its relationship with autoimmunity and cytokines using the autologous serum skin test (ASST)...

    • Source: Advances in Dermatology and Allergology
    Journals
    Journal
    31/03/19

    Development of an aggregate-selective, human-derived α-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models.

    Aggregation of alpha-synuclein (alpha-syn) is neuropathologically and genetically linked to Parkinson's disease (PD). Since stereotypic cell-to-cell spreading of alpha-syn pathology is believed to contribute to disease progression...

    • Source: Neurobiology of Disease
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    Drug news
    30/11/22

    FDA 510(k) Premarket Clearance for PainShield Plus to treat chronic pain

    NanoVibronix, Inc., medical device company utilizing the Company's proprietary and patented low intensity surface acoustic wave (SAW) technology, announced FDA 510(k) clearance of its PainShield MD PLUS, its dual-actuator ultrasound pain therapy device

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