At ASCO GU, Karim Fizazi reports PEACE-2 results showing cabazitaxel adds no benefit to ADT and radiotherapy in very high-risk prostate cancer.
Researchers developed monoclonal antibodies against Epstein-Barr virus proteins and found one prevented infection in mice with human immune systems. In separate findings, investigators detected higher levels of microplastics in prostate tumors than in adjacent noncancerous tissue.
Researchers found red blood cells acted as glucose sinks in low-oxygen conditions and that an experimental drug reversed high blood sugar in diabetic mice. In separate findings, mouse studies linked post-exercise activity of specific hypothalamic neurons to improvements in endurance.
A mid-stage trial found Moderna's combination mRNA influenza-COVID vaccine produced durable immune responses through six months in healthy adults. In separate findings, a mouse study linked non-celiac gluten sensitivity to microbiome disruptions and altered immune responses to gluten.
In a mid-stage trial, elenagen plus gemcitabine was associated with longer survival than gemcitabine alone in platinum-resistant ovarian cancer. In separate findings, an AI tool identified placenta accreta spectrum cases using ultrasound and clinical risk factors.
Researchers identified an immune-cell pathway that may contribute to influenza-related heart damage and tested an mRNA therapy targeting the process in laboratory studies. In separate findings, surgeons reported a successful live birth after temporary uterine transposition to protect fertility during pelvic radiotherapy.
WORLDSymposium 2026 data highlight AT845, AB‑1009, and ABX1100 as novel approaches for targeting disease pathways in late-onset Pompe disease.
WORLDSymposium 2026: Sustained α-Gal A expression, lyso-Gb3 reduction, and signals of renal and cardiac stability after ST-920 for Fabry disease.
Early cardiac changes, real-world data, and long-term gene therapy results from WORLDSymposium 2026 offer new clinical evidence in Fabry disease.
Newborn-screening data and advances in biochemical screening highlight how early detection and biomarker-guided follow-up shape Pompe care.
A study from Norway suggested women vaccinated against HPV may be screened for cervical cancer at longer intervals than currently recommended. In separate findings, researchers reported reduced one-year survival among U.S. cancer patients diagnosed during the first two years of the COVID-19 pandemic.
Treatment complexity and emerging options
Targeted therapies may delay ARPI resistance
From diagnostic delays to therapy decisions
A study in advanced non-small cell lung cancer found earlier-day immunotherapy infusions were associated with longer progression-free and overall survival than later treatment. In separate findings, researchers evaluated a monthly immunosuppression regimen for kidney transplant recipients and reported successful use of an artificial lung system before transplantation.
The PRIME trial provides evidence for biparametric MRI as a new standard-of-care alternative to multiparametric MRI in prostate cancer diagnosis.
Researchers identified an immune pathway involving IL-10-producing monocytes that was associated with faster pain resolution in males. In separate findings, an experimental drug targeted p53 Y220C-mutant tumors and a study linked abortion restrictions with fewer OB/GYNs.
