A US study validates the EHR‑CAT score for predicting CAT, outperforming the Khorana score and enabling more accurate risk stratification.
Researchers reported the first human use of a transcatheter coronary artery bypass procedure performed without opening the chest. Separately, new markers improved detection of circulating triple-negative breast cancer cells, and varenicline reduced cannabis use in men with cannabis use disorder.
Laboratory studies found an experimental treatment increased the proportion of viable human eggs from 47% to 71% by improving chromosome segregation during maturation. In separate findings, an experimental drug prevented and reversed metabolic liver disease and fibrosis in mice.
A study found yoga combined with buprenorphine was associated with faster recovery from opioid withdrawal than buprenorphine alone. In separate findings, researchers identified diabetes-related gene variants in Ugandans and tested an ingestible pill that signals when it has been swallowed.
An AI model trained on polysomnography data predicted risks for 130 health conditions using sleep-study recordings from a single night. In separate findings, dried blood samples from finger pricks showed agreement with Alzheimer's disease biomarker testing.
A multicenter study identified and validated a set of serum inflammatory proteins as disease‑specific biomarkers for AChR–positive MG
Researchers identified a molecular pathway linking obesity to inflammation, involving SAMHD1 inactivation, excess nucleotides and NLRP3 activation. In separate findings, an mRNA delivery system restored embryo implantation in a mouse model of endometrial injury.
An analysis found colorectal cancer became the leading cause of cancer death among U.S. adults under age 50, with mortality rising annually from 2005 through 2023. Separately, prenatal exposure to wildfire smoke during the third trimester was associated with a higher risk of autism diagnoses in children.
Abiraterone-treated high-risk mHSPC patients with rapid, sustained PSA decline showed longer PSA PFS, rPFS, and overall survival.
A prospective study found mpMRI identified more local recurrence than PSMA PET/CT in men with biochemical failure post‑prostatectomy.
A California study linked increases in zero-emission vehicle registrations with lower neighborhood nitrogen dioxide levels measured by satellite data. In separate findings, experimental contact lenses accurately monitored intraocular pressure in rabbits and transmitted data wirelessly.
Two studies found Apple Watch monitoring increased detection of atrial fibrillation and improved recognition of recurrences after catheter ablation. In separate findings, nasal saline sprays performed similarly to steroid sprays for symptom improvement in children with obstructive sleep apnea.
