Researchers identified three genes associated with differences in milk production using analyses of breast milk samples from lactating individuals. In separate findings, a three-antibody cocktail protected mice against a broad range of influenza strains, including bird flu and swine flu.
A mid-stage trial found azelastine nasal spray was associated with lower rates of COVID-19 and rhinovirus infections than placebo. Elsewhere, researchers identified a blood-protein signature that predicted ALS years before diagnosis and discovered antibodies that protected against mpox in laboratory studies.
A long-term study linked elevated high-sensitivity C-reactive protein levels in otherwise healthy women with higher lifetime risks of coronary heart disease, stroke and major cardiovascular events. In separate findings, inclisiran helped more patients achieve guideline-recommended LDL cholesterol targets when added to maximally tolerated lipid-lowering therapy.
A pooled analysis of nearly 29,000 patients with coronary artery disease found clopidogrel was associated with a lower risk of major cardiovascular or cerebrovascular events than aspirin. In separate findings, reconditioned pacemakers performed similarly to new devices in patients from low- and middle-income countries.
Cystoscopy within 6 months of TURBT is linked to lower risks of progression, cancer-specific death, and overall mortality in NMIBC.
TRANSFORM confirms liso-cel as a second-line option with curative potential in LBCL, showing durable efficacy at 3-year follow-up.
A large retrospective analysis found photorefractive keratectomy outcomes in 17- and 18-year-olds were comparable to or better than those in adults. In separate findings, extended depth of focus intraocular lenses reduced dependence on glasses after cataract surgery, while cannabis use was associated with a higher risk of type 2 diabetes.
A late-stage trial found Bayer's elinzanetant reduced the frequency and severity of menopausal hot flashes and night sweats over 52 weeks. In separate findings, researchers identified an unexpected origin for small-cell lung cancer and reported laboratory activity of a synthetic antibiotic against multidrug-resistant bacteria.
Researchers identified a CEACAM1-HuR pathway that reduced ischemia-reperfusion injury in mouse and human liver studies. In separate findings, lower exposure to nitrogen dioxide and fine particulate matter was associated with better vision in school-aged children.
An analysis detected disease-causing and antibiotic-resistant microbes in commercial raw cat food products, including shelf-stable varieties. In separate findings, researchers identified a pain-specific prostaglandin receptor and developed bioengineered capsules that reduced brain inflammation in mice.
