Xpovio approved by TGA (Australia) to treat multiple myeloma.- Antengene Corporation.
Antengene Corporation, announced that the Therapeutic Goods Administration (TGA) of the Australian Government Department of Health has registered Xpovio (selinexor) for two indications
Antengene Corporation, announced that the Therapeutic Goods Administration (TGA) of the Australian Government Department of Health has registered Xpovio (selinexor) for two indications: (1) In combination with bortezomib and dexamethasone (XBd) for the treatment of adult patients with multiple myeloma (MM) who have received at least one prior therapy and (2) in combination with dexamethasone (Xd) for the treatment of adult patients with relapsed and/or refractory multiple myeloma (R/R MM) who have received at least three prior therapies and whose disease is refractory to at least one proteasome inhibitor (PI), at least one immunomodulatory medicinal product (IMiD), and an anti-CD38 monoclonal antibody (mAb).
Xpovio is the first and only SINE approved by the TGA that helps to restore the body's own tumour suppressor pathways.
Related news and insights
The Menarini Group and Radius Health, Inc. announced that Menarini, with support from Radius, has submitted a New Drug Application (NDA) to the FDA for elacestrant in patients with ER+/HER2- advanced or metastatic breast cancer.
AstraZeneca and MSD’s Lynparza (olaparib) has been recommended for marketing authorisation in the European Union (EU) as monotherapy or in combination with endocrine therapy for the adjuvant treatment of adult patients with germline BRCA1/2 mutations (gBRCAm) who have HER2-negative high-risk early breast cancer previously treated with neoadjuvant or adjuvant chemotherapy.