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Blueprint Medicines acquires Lengo Therapeutics and with it LNG 451 , a therapy for treatment of NSCLC in patients with EGFR exon 20 insertion mutations.

Read time: 1 mins
Published: 31st Dec 2021
Blueprint Medicines Corporation announced that the company has successfully completed its previously announced acquisition of Lengo Therapeutics and lead compound LNG 451, a potential best-in-class oral precision therapy in development for the treatment of non-small cell lung cancer (NSCLC) in patients with EGFR exon 20 insertion mutations.

An investigational new drug (IND) application for LNG-451 was submitted to the FDA by Lengo Therapeutics in December 2021.

As previously disclosed, under the terms of the agreement, Blueprint Medicines acquired Lengo Therapeutics for $250 million in cash plus up to $215 million in additional potential payments based on the achievement of certain regulatory approval and sales-based milestones.

Condition: NSCLC / EGFR
Type: drug
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