Phase IV results with INVOcell fertility system published in Journal of Assisted Reproduction and Genetics- INVO Bioscience

INVO Bioscience has announced the publication of the positive results of a Phase IV trial showing the INVOcell intravaginal culture (IVC) system was equivalent to traditional In-Vitro Fertilization (IVF) incubation when comparing quality of embryos transferred and live birth rates, the primary endpoint of the trial. The results were published in the February 2016 online first issue of Journal of Assisted Reproduction and Genetics. The positive trial results were derived from a randomized, single-center, controlled trial and are the first published results to evaluate live birth rates comparing intravaginal culturing of embryos using INVOcell to traditional IVF incubation.

In the trial, the quality of day 5 embryos incubated in INVOcell was compared to traditional IVF incubated embryos. INVOcell cultured embryos were shown to be equivalent to traditional IVF embryos for embryos that were transferred. This resulted in near identical live birth rates with INVOcell generating 16 live births in 11 of 20 (55%) cycles compared to traditional IVF, which created 15 live births in 12 of 20 cycles (60%). The trial demonstrated that INVOcell is equivalent to traditional IVF incubation when comparing quality of embryos transferred and live birth rates.