Drug news
Nivolumab shows superior overall survival to dacarbazine in Melanoma trial- BMS
Bristol-Myers Squibb Company announced that a randomized blinded comparative Phase III study evaluating nivolumab versus dacarbazine (DTIC) in patients with previously untreated BRAF wild-type advanced Melanoma (CHECKMATE 066) was stopped early because an analysis conducted by the independent Data Monitoring Committee (DMC) showed evidence of superior overall survival in patients receiving nivolumab compared to the control arm. Patients in the trial will be unblinded and allowed to cross over to nivolumab. The Company will share these data with health authorities.