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MetMab fails Phase III trial for NSCLC - Genentech

Read time: 1 mins
Last updated: 4th Mar 2014
Published: 4th Mar 2014
Source: Pharmawand

Genentech announced that an independent data monitoring committee has recommended that the Phase III METLung study be stopped due to a lack of clinically meaningful efficacy. The study evaluated if onartuzumab (MetMab) in combination with Tarceva (erlotinib) helped people with previously treated, advanced Non-Small Cell Lung Cancer (NSCLC) whose tumours were identified as MET-positive live longer compared to Tarceva alone.

Overall adverse event rates were generally similar between the two groups. Data will be submitted for presentation at an upcoming medical meeting.

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