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EnVivo Pharma initiates Phase III trial for encenicline for Alzheimers

Read time: 1 mins
Last updated: 23rd Jan 2014
Published: 23rd Jan 2014
Source: Pharmawand

EnVivo Pharmaceuticals announced it has initiated COGNITIV AD, a Phase III clinical program evaluating its novel alpha-7 (alpha7) potentiator, encenicline-hydrochloride (EVP-6124), in patients with Alzheimer�s disease (AD). The program is being conducted under a Special Protocol Assessment agreement with the FDA.

Patient dosing has begun in the 26-week trial, which is designed to evaluate the safety and efficacy of two fixed doses of encenicline compared to placebo in patients with mild to moderate AD who are currently receiving stable treatment with or have been previously treated with an acetylcholinesterase inhibitor.

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