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Pivotal Study of E 2087 (Eisai) shows positive results in treating Epilepsy

Read time: 1 mins
Last updated: 19th Apr 2012
Published: 19th Apr 2012
Source: Pharmawand
A pivotal Phase III study of E 2087 (perampanel), from Eisai, developed as an adjunctive therapy for partial seizures in adult patients with Epilepsy, provides evidence that 4 and 8 mg/day doses of the drug are effective and well-tolerated in reducing uncontrolled partial-onset seizures when compared with placebo. Efficacy in seizure reduction was seen despite treatment with up to three other anti-epilepsy drugs. See: "Randomized phase III study 306: Adjunctive perampanel for refractory partial-onset seizures." G.L. Krauss et al. Neurology, April 18 2012 DOI: 10.1212/WNL.0b013e318254473
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