Drug news
KRX-0401 (Keryx/Aeterna Zentaris) fails X-PECT trial for Colorectal Cancer
Aeterna Zentaris Inc. has announced that the Phase III "X-PECT" (Xeloda + Perifosine Evaluation in Colorectal cancer Treatment) clinical trial evaluating perifosine + capecitabine (Xeloda) in patients with refractory advanced Colorectal Cancer did not meet the primary endpoint of improving overall survival versus capecitabine + placebo. The trial involving 468 patients in 65 sites in the U.S was conducted by Keryx Biopharmaceuticals, Inc. which holds the US rights as licensee.