Podcast 2
AATD genotypes involved in liver disease
Episode 2. What do genotype variations reveal about alpha-1 antitrypsin deficiency? Pavel Strnad and Jeffrey Teckman examine genotype variations underlying alpha-1 antitrypsin deficiency and how the condition presents in pediatric and adult patients. They emphasize the importance of early diagnosis and the need to identify and distinguish between patients with homozygous PiZZ and heterozygous PiMZ genotypes, given differences in comorbidities, clinical management, and outcomes.
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