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Light micrograph of a human liver stained with hematoxylin and eosin. The hepatocytes are arranged in cords separated by clear areas where hepatic sinusoids showing red blood cells are located.
Alpha-1 Antitrypsin Deficiency: Bridging Care

Assessment

Last updated: 8th Aug 2025
Published: 8th Aug 2025

Please complete the final knowledge assessment and evaluation to earn your CME credit.

1. Alpha-1 antitrypsin deficiency is caused by what process?
2. 95% of alpha-1 antitrypsin deficiency–associated liver disease cases involve what allele mutations?
3. Exposure to environmental risk factors such as tobacco and airborne toxins significantly increases the risk of developing alpha-1 antitrypsin deficiency–associated liver disease.
4. The AAT protein is involved in which physiologic process?
5. What organ systems are impacted by alpha-1 antitrypsin deficiency?
6. A person who has alpha-1 antitrypsin deficiency–associated lung disease will also have liver disease.
7. Who should be screened for alpha-1 antitrypsin deficiency?
8. How is alpha-1 antitrypsin deficiency diagnosed?
9. Approved treatment options for alpha-1 antitrypsin deficiency include which of the following?
10. Alpha-1 antitrypsin deficiency–associated liver disease is only present in adults >60 years of age?
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