Transcript
Symptoms that support the diagnosis of CIDP
Eduardo Nobile-Orazio explores the clinical symptoms that support the diagnosis of CIDP. View transcript.
Eduardo Nobile-Orazio, MD, PhD
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The diagnosis of CIDP we have always to think when we have a neuropathy that progress over weeks and months. So it is different from Guillain-Barre where you have a disease that progress and the patient get to the maximum worsening within say a few days or one week, and there is a cutoff time for the diagnosis of one month. But sometimes we have patient that they come and then you find out that the disease that they come to visit has been present to say for weeks, has been progressive for a few months. So when you have, you know, I mean I'm talking about initial diagnosis, so we always have to think about of this diagnosis whenever you have a patient who has a progressive disease which is progressing over weeks or months.
So that is the first thing. So there are not so many disease, which is a symmetric disease where a patient has a sensory impairment, paresthesia, loss of sensation, and they have weakness. And also if they have weakness which is not just distal, so affecting the hand and foot, but also they have a proximal weakness of the thigh, so they have difficulty in climb the stairs, of course difficulty running or difficulty in raising the arm is difficult, different from many neuropathy, which are mostly distally. This is a disease that affect muscle sensation proximally and distally, so that is something we have to think about this. Most of the average age of patient, you know, even they are 40, 50, but there are patient who have announced it that, you know, in their 20s, in the 30s. So that are things we have to consider.
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