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Drug information

Amitriptyline

POM
Read time: 18 mins
Last updated: 06 May 2020
Published: 13 Apr 2021

4.1 Therapeutic indications

Amitriptyline is indicated for:

• the treatment of major depressive disorder in adults

• the treatment of neuropathic pain in adults

• the prophylactic treatment of chronic tension type headache (CTTH) in adults

• the prophylactic treatment of migraine in adults

• the treatment of nocturnal enuresis in children aged 6 years and above when organic pathology, including spina bifida and related disorders, have been excluded and no response has been achieved to all other non-drug and drug treatments, including antispasmodics and vasopressin-related products.

This medicinal product should only be prescribed by a healthcare professional with expertise in the management of persistent enuresis.

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Drugs appearing in this section are approved by UK Medicines & Healthcare Products Regulatory Agency (MHRA), & the European Medicines Agency (EMA).