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Read time: 19 mins
Last updated: 06 May 2020
Published: 01 Apr 2021

4.1 Therapeutic indications

Clobazam Thame is a 1,5-benzodiazepine indicated in adults for the short-term symptomatic treatment (2-4 weeks) only of anxiety that is severe, disabling or subjecting the individual to unacceptable distress.

In treatment of anxiety states associated with affective disorders Clobazam Thame must be used only in conjunction with adequate treatments for the underlying disorder.

In patients with schizophrenic or other psychotic illnesses, use of benzodiazepines is recommended only for short term symptomatic management of hyperarousal and agitation. Benzodiazepines do not possess antipsychotic properties.

Clobazam Thame may be used as adjunctive therapy in epilepsy, in adults and children over 2 years if standard treatment with one or more anticonvulsants has failed. Treatment of simple or complex partial epilepsy with or without secondary generalisation and treatment of all types of generalised epilepsy (tonic / clonic, myoclonic, absence seizures.

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Drugs appearing in this section are approved by UK Medicines & Healthcare Products Regulatory Agency (MHRA), & the European Medicines Agency (EMA).